Spring Meeting: Coral the “4 Horses of the Apocalypse” – Aging, Pain, Depression, and Substance Abuse

Aging

Life Extension Technologies: Basic Mechanisms – Alessandro Bitto PhD, Asst Protessor, Kaeberlein Lab, UW Pathology

“Primum non Nocere”: which medications with longevity implications can be first line treatments for pain and depression? – Jon Berner MD PhD, Woodinville Psychiatric

Pain & Depression:

Effective microglia modulation in pain, depression, PTSD, long COVID, and substance abuse. (10% of brain tissue is this immune system lineage, embryonic yolk sac derived – NOT ectoderm.

Patient Panel – personal narratives and discussion or novel ettective treatments for neurointlammation

Mechanisms behind microglial modulation of synaptic pruning and trophic neuronal support – Jon Berner MD Phr Woodinville Psychiatric

Substance Abuse

Minimization of community and personal risk from self-administered opioids

• Practical conversion to monthly buprenorphine injections: clinical necessity of moving from pulsed opioid agonists, e.g. hydrocodone or fentanyl, to c fixed partial agonist serum level – Greg Sharp DO, Jacob Grillo PA-C

• Current regulatory issues DEA Diversion Control